Plinest Skin Booster is a revitalising skin booster from Italy, formulated with polynucleotides (PN), DNA molecules extracted from Italian trout using a patented Highly Purified Technology (HPT). This treatment promotes natural bio revitalisation to counter the signs of aging and super boosts the regeneration of fibroblasts and collagen to reveal youthful, glowy skin.
Plinest Skin Booster is a gel-like skin booster which is made of highly purified polynucleotides (PN-HPT®) derived safely from Italian trout DNA. Plinest provides nourishing and stimulating effects on existing fibroblasts, supporting increased collagen production and enhancing fibroblast vitality and quantity. Research also suggests that Plinest can boost skin hydration and antioxidant activity, resulting in improved skin quality overall.

The Plinest Skin Booster involves delivering Polynucleotides (PN) directly into the skin’s dermal layer, delivering these powerful molecules to the areas where they are most impactful. Polynucleotides are especially effective in promoting collagen and elastin production, proteins which are essential for maintaining skin elasticity, structure, and firmness, which naturally decline with age. This results in overall improved skin texture, elasticity, and a rejuvenated appearance.


Boosts skin volume and firmness, resulting in a bouncier, more youthful appearance.

Improves moisture retention in the skin, leading to plumpier-looking skin.

Activates skin’s natural cellular repair, leading to a smoother complexion of the skin.

Quick onset of results, visible skin enhancement in quality and texture right after treatment.






Your Plinest Skin Booster treatment will be performed by our trusted MOH-certified medical doctors. The treatment includes the doctor’s skin consultation, personalising a treatment plan for your conditions and after-care advice.

Most of our patients find the Plinest procedure comfortably tolerable. The procedure can even be done without the use of topical anaesthetic. However, for the comfort of our patients, numbing cream can be applied before the procedure. Most patients can resume their daily activities directly after the treatment.

The Plinest procedure is non-surgical, so minimal downtime is expected. Some minor redness or bruising may be visible, but they will naturally subside within a day or two. In most cases, you can comfortably resume your daily activities immediately after the treatment.

Results from Plinest Skin Booster treatments can vary for each individual. Initial improvements are often noticeable within 2 to 3 weeks following the treatment, but the full effects typically become apparent after about three months. This timeline is due to the way polynucleotides operate at a cellular level, stimulating processes such as collagen production and skin repair, which require time to become visibly evident.

The treatment is Europe CE approved and it contains highly purified Polynucleotides without any sugars or proteins or any other substances.
This minimises the risk of allergies and complications for this bio-restructuring treatment, making it a safe treatment.
The common side effects are mild swelling, bruising or redness at the injection site, which will subside within 1-2 days. For patients with thinners skin, the bumps may stay for a while longer.
Other than that, no other side effects have been reported.
The treatment can be safely combined with other energy-based treatments for optimal results by accelerating the production of collagen in the skin. Energy-based treatments that are compatible with Polynucleotide treatment:
Avoid exercising for 24 hours after treatment. Avoid extreme heat or direct sun exposure as well for at least 3 days. Avoid cosmetic products containing retinol for 3 days.